Description

7-Spiroindanyloxymorphone is a specialized synthetic opioid derivative of oxymorphone, distinguished by its unique spiroindanyl structural modification. This compound is of significant interest in advanced pharmaceutical research and development, particularly for investigating novel analgesic pathways and receptor interactions. It serves as a critical intermediate and reference standard for researchers and developers in the fields of medicinal chemistry, neuropharmacology, and analytical science.

Application

• Pharmaceutical Research & Development: A key intermediate in the synthesis of novel opioid receptor ligands and the development of new analgesic compounds.
• Medicinal Chemistry Studies: Used to study structure-activity relationships (SAR) and the impact of spirocyclic modifications on opioid receptor binding affinity and selectivity.
• Analytical Reference Standard: Serves as a high-purity standard for method development, validation, and quality control in analytical laboratories (e.g., HPLC, GC-MS).
• Neuropharmacology Research: A tool compound for investigating pain signaling pathways, receptor pharmacology, and the mechanisms of opioid action in preclinical studies.
• Chemical Synthesis: Employed as a sophisticated building block for the synthesis of more complex, targeted molecular architectures in organic chemistry.

Basic Information

Product Name	7-Spiroindanyloxymorphone
CAS No.	150380-34-0
Molecular Formula	C24H25NO4
Molecular Weight	391.46 g/mol
Synonyms	7-Spiroindanyloxymorphone; 14β-(Spiro[2H-indene-1,4'-piperidine]-1'-yl)-7,8-dihydro-4,5α-epoxy-17-methylmorphinan-3,6α-diol; 1'-((4R,4aR,7R,7aR,12bS)-3,6-dihydroxy-4a,7,9-trihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl)spiro[indene-1,4'-piperidine]; Oxymorphone spiroindanyl derivative; 7-Spiroindanyl oxymorphone
EINECS	Contact for details

Quality Control

Our 7-Spiroindanyloxymorphone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.