Description

2-Amino-5-Phenylpyridine-D5 is a deuterated analog of 2-amino-5-phenylpyridine, a valuable building block in synthetic organic chemistry. This compound is specifically designed for use as an internal standard in analytical applications, providing enhanced precision and reliability in quantitative mass spectrometry. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require high-fidelity isotopic labeling for method development, metabolic studies, and quality control.

Application

• Internal Standard for LC-MS/MS: Serves as a critical, isotopically labeled reference standard for the accurate quantification of its non-deuterated counterpart in complex biological and chemical matrices.
• Pharmaceutical Research: Used in drug metabolism and pharmacokinetics (DMPK) studies, enabling precise tracking and measurement of active pharmaceutical ingredients and their metabolites.
• Analytical Method Development: Essential for validating and calibrating sensitive analytical methods, ensuring regulatory compliance and data integrity in GLP/GMP environments.
• Isotope Dilution Mass Spectrometry (IDMS): A key component in high-precision quantitative analysis techniques, minimizing matrix effects and improving accuracy.
• Chemical Synthesis Intermediate: Acts as a deuterated synthon for the preparation of more complex labeled compounds for research and development.

Basic Information

Product Name	2-Amino-5-Phenylpyridine-D5
CAS No.	150320-81-3
Molecular Formula	C11H5D5N2
Molecular Weight	176.24 g/mol
Synonyms	2-Amino-5-phenylpyridine-d5; Deutero-2-Amino-5-phenylpyridine; (Phenyl-d5)-2-aminopyridine; 2-Pyridinamine, 5-phenyl-, pentadeuterio-; 5-Phenyl-2-pyridinamine-d5; 2-Amino-5-(pentadeuteriophenyl)pyridine; 2-AP-d5; 2-Amino-5-phenylpyridine (phenyl-d5)
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-5-Phenylpyridine-D5 is manufactured and tested under strict quality management systems. We provide comprehensive Certificates of Analysis (COA) detailing isotopic purity (D-content), chemical purity, and identity confirmation. Our quality commitment ensures the material meets the stringent requirements for use as an analytical reference standard in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.