Description

Sitostanol-5,6,22,23-D4 is a high-purity, deuterium-labeled analog of sitostanol, a plant sterol, specifically designed for advanced analytical and research applications. This stable isotope-labeled compound is essential for use as an internal standard in mass spectrometry, enabling precise quantification and metabolic studies of phytosterols. It is a critical tool for researchers and quality control laboratories in the pharmaceutical, nutraceutical, and food science industries who require the highest level of accuracy in their analytical methods. The compound is supplied with guaranteed isotopic purity and chemical stability.

Application

• Internal Standard for LC-MS/MS: Primary application for the accurate quantification of sitostanol and related phytosterols in complex biological matrices.
• Metabolic Pathway Tracing: Used in deuterium-labeling studies to investigate the absorption, distribution, metabolism, and excretion (ADME) of plant sterols.
• Pharmaceutical R&D: Supports drug development programs focused on cholesterol-lowering agents and cardiovascular health.
• Nutraceutical Analysis: Ensures precise assay of sterol content in functional foods, dietary supplements, and fortified products.
• Clinical Research: Facilitates reliable biomarker analysis in studies examining the impact of phytosterols on human lipid profiles.
• Food Safety & Quality Control: Employed in reference methods for verifying sterol claims and detecting adulteration in food products.

Basic Information

Product Name	Sitostanol-5,6,22,23-D4
CAS No.	150044-25-0
Molecular Formula	C₂₉H₄₈D₄O
Molecular Weight	~416.75 g/mol
Synonyms	24-Ethyl-5α-cholestan-3β-ol-5,6,22,23-d4; D4-Sitostanol; Stigmastanol-d4; (3β)-Stigmastan-3-ol-d4; 5,6,22,23-Tetradeutero-sitostanol; Deuterated β-Sitostanol; Isotope Labeled Sitostanol; Internal Standard Sitostanol-d4
EINECS	Contact for details

Quality Control

Every batch of Sitostanol-5,6,22,23-D4 is manufactured and analyzed under strict quality systems. We guarantee high chemical and isotopic purity, with comprehensive testing including HPLC for chemical assay and NMR/MS for isotopic enrichment verification. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, isotopic content, and confirming identity. Our quality commitment ensures data integrity for your most demanding analytical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under an inert atmosphere at -20°C to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity	≥ 98 atom % D
Chemical Purity	≥ 95% (by NMR)
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.