Description

8-Boc-3,8-Diaza-Bicyclo[3.2.1]Octane is a high-purity, protected bicyclic amine building block of significant importance in modern organic synthesis. Its core value lies in providing a rigid, nitrogen-containing scaffold that is crucial for constructing complex molecular architectures. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) targets.
• Medicinal Chemistry Scaffold: Used as a privileged structure in hit-to-lead and lead optimization campaigns to explore novel chemical space and improve drug-like properties.
• Ligand Synthesis: Employed in the preparation of sophisticated ligands for catalysis and molecular recognition applications.
• Agrochemical Research: Acts as a building block for developing novel crop protection agents and pesticides.
• Chemical Biology Probes: Utilized in the design and synthesis of tool compounds for studying biological pathways and target validation.
• Academic Research: A valuable reagent for methodological development and the synthesis of complex natural product analogs in university and institutional laboratories.

Basic Information

Product Name	8-Boc-3,8-Diaza-Bicyclo[3.2.1]Octane
CAS No.	149771-44-8
Molecular Formula	C11H20N2O2
Molecular Weight	212.29 g/mol
Synonyms	3,8-Diaza-bicyclo[3.2.1]octane-8-carboxylic acid tert-butyl ester; tert-Butyl 3,8-diazabicyclo[3.2.1]octane-8-carboxylate; 8-(tert-Butoxycarbonyl)-3,8-diazabicyclo[3.2.1]octane; 8-Boc-3,8-diazabicyclo[3.2.1]octane; BOC-DABCO; 8-N-Boc-3,8-diazabicyclo[3.2.1]octane; 149771-44-8
EINECS	Contact for details

Quality Control

Our 8-Boc-3,8-Diaza-Bicyclo[3.2.1]Octane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with full batch traceability are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.