Description

2-Iodothiophene is a versatile halogenated heterocyclic building block, specifically an iodinated derivative of thiophene. This compound is of significant value in organic synthesis, serving as a key intermediate for constructing complex molecules through cross-coupling reactions. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing thiophene or biaryl motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that incorporate the thiophene scaffold for enhanced biological activity.
• Material Science & Organic Electronics: Serves as a monomer or building block for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and semiconductors.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions such as Suzuki, Stille, and Sonogashira couplings to form carbon-carbon bonds.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D in exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	2-Iodothiophene
CAS No.	149762-92-5
Molecular Formula	C4H3IS
Molecular Weight	209.04 g/mol
Synonyms	Thiophene, 2-iodo-; 2-Iodothiophene; Iodothiophene; 2-Thienyl iodide; α-Iodothiophene; 2-Iodo-thiophene; 2-Thiophene iodide; 2-Iodo-thiophene
EINECS	Contact for details

Quality Control

Our 2-Iodothiophene is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specified parameters. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.