Description

4-Iodo-1-Benzothiophene-2-Carboximidamide Hydrochloride is a high-purity, halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceutical candidates and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly those targeting kinase inhibition or other enzyme-related pathways.
• Agrochemical Research: Used in the development of new active ingredients for crop protection, leveraging its benzothiophene core and reactive iodo/amidine groups.
• Material Science: Acts as a building block for organic electronic materials, such as organic semiconductors or charge-transport layers, due to its conjugated system.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological processes.
• Custom Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for client-specific projects requiring functionalized benzothiophene derivatives.
• Academic Research: A valuable reagent for methodological studies in cross-coupling reactions, heterocyclic chemistry, and medicinal chemistry programs at universities and institutes.

Basic Information

Product Name	4-Iodo-1-Benzothiophene-2-Carboximidamide Hydrochloride
CAS No.	149732-36-5
Molecular Formula	C9H8IN2S·HCl
Molecular Weight	338.60 g/mol
Synonyms	4-Iodobenzo[b]thiophene-2-carboximidamide hydrochloride; 1-Benzothiophene-2-carboximidamide, 4-iodo-, hydrochloride; 4-Iodo-1-benzothiophene-2-carboximidamide HCl; 4-Iodo-benzo[b]thiophene-2-carboximidamide monohydrochloride; 2-Amidino-4-iodobenzothiophene hydrochloride; 149732-36-5 (CAS); 4-Iodo-BTA hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Iodo-1-Benzothiophene-2-Carboximidamide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting standards for research and development use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere when not in use to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.