Description

(2S)-2-Amino-3-{1H-Pyrrolo[2,3-C]Pyridin-3-Yl}Propanoic Acid is a high-purity, non-proteinogenic amino acid derivative featuring a fused pyrrolopyridine heterocyclic system. This compound is of significant value as a sophisticated pharmaceutical intermediate and a key building block in medicinal chemistry research. It is primarily sought by R&D and production teams in the pharmaceutical and biotechnology sectors for the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of targeted small-molecule drugs, particularly kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Bioconjugation & Probe Development: Serves as a specialty amino acid for creating labeled peptides or molecular probes for biochemical assays.
• Peptidomimetics: Incorporated into peptide analogs to enhance metabolic stability, bioavailability, or receptor binding affinity.
• Chemical Biology Tools: Utilized in the development of enzyme inhibitors or modulators for probing biological pathways.
• Reference Standard: Sourced for analytical method development, validation, and quality control in API manufacturing.

Basic Information

Product Name	(2S)-2-Amino-3-{1H-Pyrrolo[2,3-C]Pyridin-3-Yl}Propanoic Acid
CAS No.	149704-63-2
Molecular Formula	C10H11N3O2
Molecular Weight	205.21 g/mol
Synonyms	(S)-2-Amino-3-(1H-pyrrolo[2,3-c]pyridin-3-yl)propanoic acid; 3-(1H-Pyrrolo[2,3-c]pyridin-3-yl)-L-alanine; L-3-(1H-Pyrrolo[2,3-c]pyridin-3-yl)alanine; 1H-Pyrrolo[2,3-c]pyridine-3-propanoic acid, α-amino-, (S)-; 149704-63-2; (S)-α-Amino-1H-pyrrolo[2,3-c]pyridine-3-propanoic acid; 7-Azatryptophan analog
EINECS	Contact for details

Quality Control

Our production of (2S)-2-Amino-3-{1H-Pyrrolo[2,3-C]Pyridin-3-Yl}Propanoic Acid adheres to stringent quality management protocols. Every batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing comprehensive specifications are provided with each shipment. We support compliance requirements for cGMP, ISO, and other relevant regulatory frameworks for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. For long-term storage, consider desiccated environments.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.