Description

tert-Butyl 2-Iodothiophen-3-Ylcarbamate is a high-purity, specialized organic intermediate of significant value in advanced chemical synthesis. This compound matters for its role as a key building block in the development of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. Industries that require this product include pharmaceutical R&D for active pharmaceutical ingredient (API) development, agrochemical research for novel crop protection agents, and academic institutions engaged in heterocyclic and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those containing functionalized thiophene scaffolds.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the iodine moiety for further functionalization.
• Material Science: Serves as a precursor for organic electronic materials and functional polymers where the thiophene unit is essential.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, or Sonogashira couplings.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and library synthesis for drug discovery programs.
• Chemical Biology: Used as a probe or labeling agent due to the reactive halogen handle.

Basic Information

Product Name	tert-Butyl 2-Iodothiophen-3-Ylcarbamate
CAS No.	149704-10-9
Molecular Formula	C9H12INO2S
Molecular Weight	325.17 g/mol
Synonyms	tert-Butyl N-(2-iodothiophen-3-yl)carbamate; 2-Iodo-3-((tert-butoxycarbonyl)amino)thiophene; 3-((tert-Butoxycarbonyl)amino)-2-iodothiophene; tert-Butyl (2-iodo-3-thienyl)carbamate; 2-Iodo-thiophene-3-carboxylic acid tert-butylamide (related); Boc-2-Iodo-3-aminothiophene; BOC-2I-3AT; tert-Butyl 2-iodo-3-aminothiophene carbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Iodothiophen-3-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.