Description

1H-Indole-3-Propanoic Acid, 5-Cyano- is a high-purity synthetic intermediate of significant interest in advanced organic synthesis. This compound, with CAS number 149681-66-3, is valued for its indole core functionalized with a cyano group and a propanoic acid side chain, offering versatile reactivity. It is primarily sought after by research institutions and pharmaceutical development companies for the synthesis of novel bioactive molecules and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Key building block for the research and development of new drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the creation of advanced plant growth regulators and novel pesticide formulations.
• Biochemical Research: Serves as a precursor or standard in studies involving tryptophan metabolism and indole alkaloid biosynthesis.
• Material Science: Potential monomer or functional additive in the synthesis of specialized polymers and organic electronic materials.
• Academic & Contract Research: Essential reagent for methodological development in organic chemistry and for custom synthesis projects.

Basic Information

Product Name	1H-Indole-3-Propanoic Acid, 5-Cyano-
CAS No.	149681-66-3
Molecular Formula	C₁₂H₁₀N₂O₂
Molecular Weight	214.22 g/mol
Synonyms	5-Cyanoindole-3-propionic Acid; 3-(5-Cyano-1H-indol-3-yl)propanoic Acid; 5-Cyano-1H-indole-3-propanoic Acid; 5-CN-IPA; 5-Cyanoindole-3-propanoic Acid; (5-Cyano-1H-indol-3-yl)propanoic Acid; 5-Cyano-1H-indole-3-propionic Acid
EINECS	Contact for details

Quality Control

Our 1H-Indole-3-Propanoic Acid, 5-Cyano- is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product may be light-sensitive and should be handled accordingly.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.