Description

6-Methyl-3-Piperidin-4-Yl-1H-Indole is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel therapeutic agents. It is primarily required by research institutions and pharmaceutical companies engaged in the development of central nervous system (CNS) and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates targeting neurological receptors.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Synthesis: Serves as a versatile building block for constructing complex indole- and piperidine-containing libraries for high-throughput screening.
• Biochemical Research: Employed in the study of enzyme inhibition and receptor-ligand interactions due to its specific molecular architecture.
• Contract Manufacturing (CMO): Supplied to custom synthesis organizations for the production of Active Pharmaceutical Ingredients (APIs) under GMP conditions.

Basic Information

Product Name	6-Methyl-3-Piperidin-4-Yl-1H-Indole
CAS No.	149669-45-4
Molecular Formula	C15H20N2
Molecular Weight	228.34 g/mol
Synonyms	4-(6-Methyl-1H-indol-3-yl)piperidine; 6-Methyl-3-(4-piperidyl)indole; 3-(4-Piperidinyl)-6-methyl-1H-indole; 6-Methyl-3-(piperidin-4-yl)-1H-indole; 1H-Indole, 6-methyl-3-(4-piperidinyl)-; 149669-45-4
EINECS	Contact for details

Quality Control

Our production of 6-Methyl-3-Piperidin-4-Yl-1H-Indole adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide detailed Certificates of Analysis (COA) with each shipment, ensuring traceability and compliance with research-grade and GMP-starting material standards as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.