Description

5-Fluoro-3-Piperidin-4-Yl-1H-Indole is a high-value, heterocyclic organic compound featuring a fused indole and piperidine scaffold with a strategic fluorine substitution. This molecular architecture makes it a critical advanced pharmaceutical intermediate for medicinal chemistry research and drug discovery programs. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, and other therapeutic areas.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization due to its privileged indole-piperidine hybrid structure.
• Biochemical Tool Compound: Serves as a precursor or reference standard in the development of biochemical probes for studying enzyme or receptor interactions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of complex molecules for clinical trials.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis methodologies and novel heterocycle chemistry.

Basic Information

Product Name	5-Fluoro-3-Piperidin-4-Yl-1H-Indole
CAS No.	149669-43-2
Molecular Formula	C13H15FN2
Molecular Weight	218.27 g/mol
Synonyms	4-(5-Fluoro-1H-indol-3-yl)piperidine; 5-Fluoro-3-(4-piperidinyl)-1H-indole; 3-(Piperidin-4-yl)-5-fluoro-1H-indole; 5-Fluoro-3-piperidin-4-ylindole; 1H-Indole, 5-fluoro-3-(4-piperidinyl)-; 149669-43-2; 5-Fluoro-3-(4-piperidyl)-1H-indole
EINECS	Contact for details

Quality Control

Our 5-Fluoro-3-Piperidin-4-Yl-1H-Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.