Description

4-[(4-Chlorophenyl)Thio]Thiophene-3-Carboxylic Acid is a high-purity, specialized organic building block of significant interest in advanced chemical synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific thiophene and arylthioether functionalities into their target molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, or infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, where the thiophene-carboxylic acid moiety can contribute to biological activity.
• Material Science Precursor: Acts as a monomer or functionalizing agent in the creation of conductive polymers, organic semiconductors, or nonlinear optical (NLO) materials.
• Ligand Synthesis: Utilized for preparing novel ligands in coordination chemistry and catalysis, leveraging the sulfur and carboxylic acid functional groups for metal binding.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific custom synthesis projects.

Basic Information

Product Name	4-[(4-Chlorophenyl)Thio]Thiophene-3-Carboxylic Acid
CAS No.	149609-86-9
Molecular Formula	C11H7ClO2S2
Molecular Weight	270.76 g/mol
Synonyms	3-Thiophenecarboxylic acid, 4-[(4-chlorophenyl)thio]-; 4-[(4-Chlorophenyl)sulfanyl]thiophene-3-carboxylic acid; 4-(4-Chlorophenylsulfanyl)thiophene-3-carboxylic acid; 4-(p-Chlorophenylthio)thiophene-3-carboxylic acid; 149609-86-9; Thiophene-3-carboxylic acid, 4-[(4-chlorophenyl)thio]-; 4-(4-Chlorobenzene-1-sulfonyl)thiophene-3-carboxylic acid (related); 4-(4-Chlorophenylthio)-3-thiophenecarboxylic acid
EINECS	Contact for details

Quality Control

Our 4-[(4-Chlorophenyl)Thio]Thiophene-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed to protect the contents from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.