Description

2-Amino-4-Cyclohexyl-Thiophene-3-Carboxylic Acid Ethyl Ester is a high-value, multifunctional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines a thiophene ring with amino and ester functionalities, making it a versatile precursor for constructing complex pharmacophores and specialty materials. This compound is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and material science industries for the creation of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in therapeutic areas targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Serves as a core structure for designing new generation pesticides, herbicides, and fungicides with improved efficacy and environmental profiles.
• Material Science Precursor: Used in the synthesis of advanced organic electronic materials, such as organic semiconductors and conductive polymers, due to the electron-rich thiophene moiety.
• Chemical Biology Probe Development: Employed in medicinal chemistry to create tool compounds and probes for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
• Academic & Industrial R&D: Fundamental building block for methodological research in heterocyclic and organosulfur chemistry within university and corporate laboratories.

Basic Information

Product Name	2-Amino-4-Cyclohexyl-Thiophene-3-Carboxylic Acid Ethyl Ester
CAS No.	149588-08-9
Molecular Formula	C13H19NO2S
Molecular Weight	253.36 g/mol
Synonyms	Ethyl 2-Amino-4-cyclohexylthiophene-3-carboxylate; 4-Cyclohexyl-2-aminothiophene-3-carboxylic Acid Ethyl Ester; 2-Amino-4-cyclohexyl-3-thiophenecarboxylic Acid Ethyl Ester; 2-Amino-4-cyclohexylthiophene-3-carboxylic Acid Ethyl Ester; 149588-08-9; 3-Thiophenecarboxylic acid, 2-amino-4-cyclohexyl-, ethyl ester; AKOS BRN-0791; SCHEMBL188830
EINECS	Contact for details

Quality Control

Our 2-Amino-4-Cyclohexyl-Thiophene-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports your R&D and scale-up processes with reliable, high-purity material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.