Description

2(1H)-Isoquinolinecarboxylic Acid, 7-Cyano-3,4-Dihydro-, 1,1-Dimethylethyl Ester is a high-purity, synthetically valuable chemical intermediate characterized by its functionalized isoquinoline core. This compound is critical for advanced organic synthesis, particularly in the development of complex molecules with targeted biological activity. It is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used extensively in lead optimization and structure-activity relationship (SAR) studies due to its versatile chemical scaffold.
• Agrochemical Development: Acts as a precursor in the research and synthesis of new crop protection agents and herbicides.
• Organic Synthesis: Employed in academic and industrial laboratories for constructing complex heterocyclic compounds and natural product analogs.
• Chemical Biology Probes: Utilized in the development of molecular probes and diagnostic agents for biological research.

Basic Information

Product Name	2(1H)-Isoquinolinecarboxylic Acid, 7-Cyano-3,4-Dihydro-, 1,1-Dimethylethyl Ester
CAS No.	149354-03-0
Molecular Formula	C15H16N2O2
Molecular Weight	256.30 g/mol
Synonyms	tert-Butyl 7-cyano-3,4-dihydroisoquinoline-2(1H)-carboxylate; 7-Cyano-1,2,3,4-tetrahydroisoquinoline-2-carboxylic acid tert-butyl ester; 7-Cyano-3,4-dihydro-2(1H)-isoquinolinecarboxylic acid 1,1-dimethylethyl ester; Boc-7-cyano-1,2,3,4-tetrahydroisoquinoline; 7-Cyano-Tic-OtBu; tert-Butyl 7-cyano-1,2,3,4-tetrahydroisoquinoline-2-carboxylate; 7-CN-Tic-OtBu
EINECS	Contact for details

Quality Control

Our production of 2(1H)-Isoquinolinecarboxylic Acid, 7-Cyano-3,4-Dihydro-, 1,1-Dimethylethyl Ester adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer requirements for research or cGMP-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.