Description

5-Chloro-n-(3-Morpholin-4-Ylpropyl)-2-Nitro-Benzothiophen-3-Amine is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters for its critical role as a key building block in the synthesis of novel, high-value active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular design. Pharmaceutical R&D teams and fine chemical manufacturers need this precise intermediate to develop next-generation drug candidates, ensuring process consistency and regulatory compliance from early development to commercial scale. The CAS number for this product is 149338-22-7.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic research.
• Chemical Biology Probe Development: Used in medicinal chemistry to create targeted molecular probes for studying protein interactions and biological pathways.
• Organic Synthesis Building Block: Provides a functionalized benzothiophene core for constructing complex heterocyclic libraries in combinatorial chemistry.
• Agrochemical Research: Acts as an intermediate in the development of new crop protection agents with specific modes of action.
• Material Science Applications: Potential use in the synthesis of organic semiconductors or specialty polymers due to its electron-rich structure.

Basic Information

Product Name	5-Chloro-n-(3-Morpholin-4-Ylpropyl)-2-Nitro-Benzothiophen-3-Amine
CAS No.	149338-22-7
Molecular Formula	C15H18ClN3O3S
Molecular Weight	355.84 g/mol
Synonyms	5-Chloro-N-(3-morpholinopropyl)-2-nitrobenzo[b]thiophen-3-amine; 3-Amino-5-chloro-N-(3-morpholinopropyl)-2-nitrobenzo[b]thiophene; 149338-22-7; 5-Chloro-2-nitro-N-(3-morpholin-4-ylpropyl)-1-benzothiophen-3-amine; Benzo[b]thiophen-3-amine, 5-chloro-N-(3-morpholinopropyl)-2-nitro-; 5-Chloro-N-(3-morpholin-4-yl-propyl)-2-nitro-benzo[b]thiophen-3-ylamine
EINECS	Contact for details

Quality Control

Our 5-Chloro-n-(3-Morpholin-4-Ylpropyl)-2-Nitro-Benzothiophen-3-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and support your regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.