Description

Benzo(B)Thiophen-3-Amine, 2-Nitro-n-(3-(Trifluoromethyl)Phenyl)- is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure incorporating a nitro group and a trifluoromethylphenyl moiety. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting a range of therapeutic areas. It is primarily sought by pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those requiring a benzothiophene core for bioactivity.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides where the specific substitution pattern can influence biological activity.
• Material Science Precursor: Serves as a starting material for creating specialized organic electronic materials or ligands for catalysis.
• Chemical Biology Probes: Utilized in academic and industrial research to develop molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: Employed by CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this precise chemical scaffold.

Basic Information

Product Name	Benzo(B)Thiophen-3-Amine, 2-Nitro-n-(3-(Trifluoromethyl)Phenyl)-
CAS No.	149338-13-6
Molecular Formula	C15H9F3N2O2S
Molecular Weight	338.31 g/mol
Synonyms	2-Nitro-N-[3-(trifluoromethyl)phenyl]-1-benzothiophen-3-amine; 1-Benzothiophen-3-amine, 2-nitro-N-[3-(trifluoromethyl)phenyl]-; N-(3-(Trifluoromethyl)phenyl)-2-nitrobenzo[b]thiophen-3-amine; 2-Nitro-N-(3-trifluoromethylphenyl)benzo[b]thiophen-3-amine; 149338-13-6; 2-Nitro-N-(α,α,α-trifluoro-m-tolyl)-1-benzothiophen-3-amine
EINECS	Contact for details

Quality Control

Every batch of Benzo(B)Thiophen-3-Amine, 2-Nitro-n-(3-(Trifluoromethyl)Phenyl)- undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation, and impurity profiles is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids, bases, and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.