Description

Ethyl 6-Bromo-2-(Bromomethyl)-5-Hydroxy-1-Methyl-1H-Indole-3-Carboxylate is a high-value, multi-functional brominated indole derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its molecular architecture, featuring reactive bromomethyl and ester groups, makes it an indispensable building block for constructing complex heterocyclic frameworks. This compound is primarily sought after by pharmaceutical R&D and fine chemical synthesis laboratories for the development of novel active pharmaceutical ingredients (APIs) and specialized agrochemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex indole-based drug candidates, particularly for targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides with novel modes of action.
• Material Science Research: Serves as a monomer or functional unit in the development of advanced organic electronic materials and dyes.
• Academic & R&D: A valuable reagent for methodological studies in organic synthesis, including cross-coupling reactions and heterocycle construction.
• Bioconjugation & Probe Development: The reactive bromomethyl group allows for attachment to biomolecules, useful in creating diagnostic probes or targeted drug delivery systems.

Basic Information

Product Name	Ethyl 6-Bromo-2-(Bromomethyl)-5-Hydroxy-1-Methyl-1H-Indole-3-Carboxylate
CAS No.	149246-36-6
Molecular Formula	C14H15Br2NO3
Molecular Weight	405.08 g/mol
Synonyms	Ethyl 6-bromo-2-(bromomethyl)-5-hydroxy-1-methylindole-3-carboxylate; 1H-Indole-3-carboxylic acid, 6-bromo-2-(bromomethyl)-5-hydroxy-1-methyl-, ethyl ester; 6-Bromo-2-(bromomethyl)-5-hydroxy-1-methyl-1H-indole-3-carboxylic acid ethyl ester; 149246-36-6; AI3-63500; SCHEMBL2188491; ZINC000095909786; AKOS040757186
EINECS	Contact for details

Quality Control

Our production of Ethyl 6-Bromo-2-(Bromomethyl)-5-Hydroxy-1-Methyl-1H-Indole-3-Carboxylate adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. Our quality management system is designed to meet the exacting standards of pharmaceutical and advanced synthetic chemistry applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed when not in use to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.