Description

10-Chloro-7-Thia-2,5-Diazatricyclo[6.4.0.0^{2,6}]Dodeca-1(8),3,5,9,11-Pentaene-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant commercial value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within the fields of oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug candidates and novel chemical entities (NCEs).
• Research & Development (R&D): Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: A key building block for constructing the core scaffold of target APIs, especially those with fused tricyclic systems.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.
• Chemical Biology: Utilized in the development of chemical probes for studying biological pathways and target validation.

Basic Information

Product Name	10-Chloro-7-Thia-2,5-Diazatricyclo[6.4.0.0^{2,6}]Dodeca-1(8),3,5,9,11-Pentaene-4-Carboxylic Acid
CAS No.	149210-29-7
Molecular Formula	C11H5ClN2O2S
Molecular Weight	264.68 g/mol
Synonyms	10-Chloro-7-thia-2,5-diazatricyclo[6.4.0.0^{2,6}]dodeca-1(8),3,5,9,11-pentaene-4-carboxylic acid; 4-Carboxy-10-chloro-7-thia-2,5-diazatricyclo[6.4.0.0^{2,6}]dodeca-1(8),3,5,9,11-pentaene; 10-Chloro-7-thia-2,5-diazatricyclo[6.4.0.0²,⁶]dodeca-1(8),3,5,9,11-pentaene-4-carboxylic acid; CAS 149210-29-7; 10-Chloro-7-thia-2,5-diazatricyclo[6.4.0.0(2,6)]dodeca-1(8),3,5,9,11-pentaene-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 10-Chloro-7-Thia-2,5-Diazatricyclo[6.4.0.0^{2,6}]Dodeca-1(8),3,5,9,11-Pentaene-4-Carboxylic Acid adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support development and commercial projects with material produced under quality guidelines suitable for pharmaceutical R&D and non-GMP/GLP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and hygroscopic; therefore, containers should be kept sealed under an inert atmosphere when not in use to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.