Description

n-(p-Toluenesulfonyl)Indole-3-Boronic Acid is a high-value, multi-functional organoboron building block used in advanced organic synthesis. This compound is critical for facilitating efficient carbon-carbon bond formation, enabling the creation of complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications in medicinal chemistry, catalyst development, and the synthesis of novel heterocyclic compounds.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for constructing biaryl and heterobiaryl systems, which are core scaffolds in many active pharmaceutical ingredients (APIs) and agrochemicals.
• Medicinal Chemistry & Drug Discovery: Used in the synthesis of indole-based drug candidates, including kinase inhibitors, receptor modulators, and antiviral agents.
• Agrochemical Intermediate: Serves as a precursor in the development of novel herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Material Science Research: Employed in the synthesis of organic semiconductors, conductive polymers, and luminescent materials for optoelectronic devices.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing specialized fine chemicals.

Basic Information

Product Name	n-(p-Toluenesulfonyl)Indole-3-Boronic Acid
CAS No.	149108-61-2
Molecular Formula	C15H14BNO4S
Molecular Weight	315.15 g/mol
Synonyms	1-(4-Methylphenyl)sulfonyl-1H-indole-3-boronic acid; 3-Borono-1-(p-tolylsulfonyl)indole; 1-Tosyl-1H-indole-3-boronic acid; N-Tosylindole-3-boronic acid; 1-(Toluene-4-sulfonyl)-1H-indole-3-boronic acid; Indole-3-boronic acid N-tosyl derivative; B-[1-[(4-Methylphenyl)sulfonyl]-1H-indol-3-yl]boronic acid
EINECS	Contact for details

Quality Control

Our n-(p-Toluenesulfonyl)Indole-3-Boronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation and hydrolysis. Keep away from heat and incompatible materials. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.