Description

Ethyl 4-Chloro-2,5-Dimethylthieno[2,3-D]Pyrimidine-6-Carboxylate is a high-value heterocyclic building block and advanced pharmaceutical intermediate. This compound is critical for the synthesis of complex molecules, offering a versatile scaffold for medicinal chemistry research and development. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of active pharmaceutical ingredients (APIs) and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting kinase inhibition and other enzymatic pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Used in the construction of complex fused-ring systems and functionalized heterocycles for advanced material science.
• Agrochemical Development: Potential intermediate in the research and synthesis of novel crop protection agents and pesticides.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and process development for the life sciences industry.

Basic Information

Product Name	Ethyl 4-Chloro-2,5-Dimethylthieno[2,3-D]Pyrimidine-6-Carboxylate
CAS No.	148838-70-4
Molecular Formula	C11H11ClN2O2S
Molecular Weight	270.73 g/mol
Synonyms	Ethyl 4-Chloro-2,5-dimethylthieno[2,3-d]pyrimidine-6-carboxylate; 4-Chloro-2,5-dimethylthieno[2,3-d]pyrimidine-6-carboxylic acid ethyl ester; Thieno[2,3-d]pyrimidine-6-carboxylic acid, 4-chloro-2,5-dimethyl-, ethyl ester; 148838-70-4; Ethyl 4-chloro-2,5-dimethylthienopyrimidine-6-carboxylate; 4-Chloro-2,5-dimethyl-6-(ethoxycarbonyl)thieno[2,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our Ethyl 4-Chloro-2,5-Dimethylthieno[2,3-D]Pyrimidine-6-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.