Description

Tecalcet CAS NO 148717-49-1 is a high-purity synthetic compound, also known as a calcimimetic agent, designed for advanced pharmaceutical research and development. Its primary value lies in its ability to modulate calcium-sensing receptors, making it a critical intermediate for developing novel therapeutic agents. This product is essential for pharmaceutical manufacturers and research institutions focused on metabolic bone disorders, hyperparathyroidism, and related endocrine conditions.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs) for calcimimetic drugs.
• Research & Development: Used in preclinical and clinical research for studying calcium homeostasis and receptor pharmacology.
• Metabolic Disorder Therapeutics: A critical component in the development of treatments for secondary hyperparathyroidism, particularly in patients with chronic kidney disease.
• Endocrinology Studies: Employed in biochemical assays and studies targeting the calcium-sensing receptor (CaSR).
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.
• Process Chemistry: Applied in scale-up and optimization of synthetic routes for related therapeutic compounds.

Basic Information

Product Name	Tecalcet
CAS No.	148717-49-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Tecalcet Hydrochloride; AMG 073; Cinacalcet Impurity; Calcimimetic Agent; N-[(1R)-1-(1-Naphthyl)ethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine; (R)-N-[1-(1-Naphthyl)ethyl]-3-[3-(trifluoromethyl)phenyl]propylamine; Sensipar Related Compound
EINECS	Contact for details

Quality Control

Our Tecalcet is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, IR for identification, and residual solvent analysis. We provide full traceability and support regulatory submissions. A detailed Certificate of Analysis (COA) is supplied with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from moisture and direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.