Description

1H-Indole-2-Propanoic Acid, 1-[(4-Chlorophenyl)Methyl]-3-[(1,1-Dimethylethyl)Thio]-5-Hydroxy-α,α-Dimethyl- is a high-purity, synthetically derived indole derivative of significant interest in advanced organic synthesis. This compound serves as a critical building block and key intermediate for researchers and process chemists developing novel active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily utilized by the pharmaceutical, agrochemical, and academic research sectors where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological or metabolic pathways.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its complex heterocyclic structure.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses to introduce the indole core with specific substitutions.
• Material Science Research: Potential intermediate for synthesizing specialized organic electronic materials or ligands for catalysts.

Basic Information

Item	Details
Product Name	1H-Indole-2-Propanoic Acid, 1-[(4-Chlorophenyl)Methyl]-3-[(1,1-Dimethylethyl)Thio]-5-Hydroxy-α,α-Dimethyl-
CAS No.	148693-71-4
Molecular Formula	C24H28ClNO3S
Molecular Weight	445.99 g/mol
Synonyms	5-Hydroxy-1-[(4-chlorophenyl)methyl]-3-(tert-butylthio)-α,α-dimethyl-1H-indole-2-propanoic acid; 1-[(4-Chlorobenzyl)-3-(tert-butylthio)-5-hydroxy-α,α-dimethyl-1H-indole-2-propanoic Acid; Tert-Butyl 5-hydroxy-1-(4-chlorobenzyl)-α,α-dimethyl-2-(2-carboxyethyl)indole-3-yl sulfide; 148693-71-4; A substituted indole-2-propanoic acid derivative.
EINECS	Contact for details

Quality Control

Our 1H-Indole-2-Propanoic Acid derivative is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.