Description

Bicyclo[2.2.1]Heptane-2-Carbonitrile, 2-Hydroxy-6-Methyl-, (2-Endo,6-Exo)- (9Ci) is a high-purity, stereochemically defined bicyclic nitrile derivative that serves as a critical chiral building block and advanced pharmaceutical intermediate. Its unique fused ring structure and functional groups make it invaluable for synthesizing complex molecules with precise three-dimensional architecture. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the production of advanced, stereoselective pesticides and herbicides where specific spatial orientation is crucial for bioactivity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing novel chiral ligands and organocatalysts used in enantioselective synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring complex bicyclic frameworks.
• Academic & Industrial Research: A valuable compound for methodological studies in organic synthesis, including cycloaddition reactions and functional group transformations.
• Material Science Monomer: Potential use as a monomer for creating polymers with unique thermal and mechanical properties derived from its rigid norbornane skeleton.

Basic Information

Product Name	Bicyclo[2.2.1]Heptane-2-Carbonitrile, 2-Hydroxy-6-Methyl-, (2-Endo,6-Exo)- (9Ci)
CAS No.	148683-89-0
Molecular Formula	C9H13NO
Molecular Weight	151.21 g/mol
Synonyms	(2-Endo,6-Exo)-2-Hydroxy-6-methylbicyclo[2.2.1]heptane-2-carbonitrile; 2-Hydroxy-6-methyl-2-norbornanecarbonitrile (endo,exo); 6-Methyl-2-norbornanecarbonitrile-2-ol; 2-Cyano-2-hydroxy-6-methylnorbornane; Bicyclo[2.2.1]heptane-2-carbonitrile, 2-hydroxy-6-methyl-, (1S,2R,4S)-rel-; (1R,2S,4R)-2-Hydroxy-6-methylbicyclo[2.2.1]heptane-2-carbonitrile
EINECS	Contact for details

Quality Control

Every batch of Bicyclo[2.2.1]Heptane-2-Carbonitrile, 2-Hydroxy-6-Methyl-, (2-Endo,6-Exo)- (9Ci) is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including chiral purity analysis, to ensure compliance with exacting customer specifications and industry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.