Description

Isophthalic-2,4,5,6-D4 Acid is a deuterium-labeled isotopologue of isophthalic acid, where four hydrogen atoms are replaced with deuterium. This compound is essential as a stable isotope-labeled internal standard for precise quantitative analysis in mass spectrometry and NMR spectroscopy. It is primarily required by analytical laboratories, pharmaceutical researchers, and chemical manufacturers involved in method development, metabolic studies, and quality control of complex organic materials.

Application

• Internal Standard for Quantitative Analysis: Serves as a critical reference standard in LC-MS, GC-MS, and NMR for accurate quantification of isophthalic acid and related compounds.
• Pharmaceutical Research: Used in drug metabolism and pharmacokinetics (DMPK) studies to trace and quantify metabolites.
• Polymer Science Research: Acts as a tracer in the study of polymerization mechanisms and the degradation pathways of polyesters and polyamides.
• Environmental Analysis: Employed in the detection and measurement of phthalate derivatives or related aromatic acids in environmental samples.
• Chemical Synthesis: Utilized as a labeled building block for the synthesis of more complex deuterated compounds for research purposes.

Basic Information

Product Name	Isophthalic-2,4,5,6-D4 Acid
CAS No.	148472-48-4
Molecular Formula	C8H2D4O4
Molecular Weight	170.16 g/mol
Synonyms	1,3-Benzenedicarboxylic-2,4,5,6-d4 Acid; Deuterated Isophthalic Acid; Isophthalic Acid-d4; IPA-d4; Benzene-1,3-dicarboxylic-d4 Acid; m-Phthalic-d4 Acid; 1,3-Dicarboxybenzene-d4; m-Benzenedicarboxylic-d4 Acid
EINECS	Contact for details

Quality Control

Our Isophthalic-2,4,5,6-D4 Acid is produced under strict quality protocols to ensure high isotopic purity and chemical integrity, suitable for sensitive analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and analytical results. We adhere to relevant standards for high-purity reference materials to ensure reliable and reproducible performance in your laboratory.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Isotopic Purity (D-content)	≥ 98 atom % D
Chemical Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.