Description

Methyl 5-Chloro-1-Methyl-1H-Indole-2-Carboxylate is a high-purity, synthetically valuable indole derivative that serves as a critical building block in advanced organic synthesis. Its core value lies in providing a functionalized indole scaffold essential for constructing complex molecules with targeted biological activity. This intermediate is primarily needed by pharmaceutical R&D and fine chemical manufacturers engaged in developing new active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and plant growth regulators that utilize the indole core structure.
• Material Science Research: Employed in the development of organic semiconductors, photochromic materials, and advanced polymers due to its electron-rich heterocyclic system.
• Biochemical Tool Compound: Serves as a starting material for creating fluorescent probes, enzyme inhibitors, and other research chemicals for life science studies.
• Custom Synthesis & Contract Manufacturing: A vital substrate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	Methyl 5-Chloro-1-Methyl-1H-Indole-2-Carboxylate
CAS No.	148356-79-0
Molecular Formula	C11H10ClNO2
Molecular Weight	223.66 g/mol
Synonyms	5-Chloro-1-methyl-1H-indole-2-carboxylic acid methyl ester; Methyl 5-chloro-1-methylindole-2-carboxylate; 1-Methyl-5-chloroindole-2-carboxylic acid methyl ester; 2-Carbomethoxy-5-chloro-1-methylindole; 148356-79-0; 5-Chloro-1-methylindole-2-carboxylic acid methyl ester; Methyl (5-chloro-1-methyl-1H-indol-2-yl)carboxylate
EINECS	Contact for details

Quality Control

Our production of Methyl 5-Chloro-1-Methyl-1H-Indole-2-Carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for your synthetic processes. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR to confirm identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single unknown impurity	≤0.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.