Description

5-(6,7-Dimethoxy-1,2,3,4-Tetrahydro-Isoquinolin-1-Yl)-Pentan-1-Ol Hydrochloride is a high-purity, synthetic organic compound belonging to the tetrahydroisoquinoline class, valued for its role as a key pharmaceutical intermediate. Its molecular structure makes it a versatile building block for the research and development of bioactive molecules targeting the central nervous system. This compound is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of potential therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those with neurological or cardiovascular activity.
• Biochemical Research: Used as a reference standard or a starting material in pharmacological studies to investigate receptor binding and enzyme inhibition.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses to construct more elaborate heterocyclic frameworks common in medicinal chemistry.
• Academic Research: Utilized in university and institutional labs for methodological development and the exploration of new chemical entities.
• Process Chemistry Development: Serves as a model compound for scaling up synthetic routes under current Good Manufacturing Practice (cGMP) conditions.

Basic Information

Product Name	5-(6,7-Dimethoxy-1,2,3,4-Tetrahydro-Isoquinolin-1-Yl)-Pentan-1-Ol Hydrochloride
CAS No.	148204-37-9
Molecular Formula	C₁₆H₂₆ClNO₃
Molecular Weight	315.84 g/mol
Synonyms	1-(5-Hydroxypentyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride; 5-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-1-yl)pentan-1-ol hydrochloride; 6,7-Dimethoxy-1-(5-hydroxypentyl)-1,2,3,4-tetrahydroisoquinoline HCl; 1-(5-Hydroxypentyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline HCl; 148204-37-9; DTXI; THIQ derivative hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 5-(6,7-Dimethoxy-1,2,3,4-Tetrahydro-Isoquinolin-1-Yl)-Pentan-1-Ol Hydrochloride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, supporting cGMP-compliant development work. A detailed Certificate of Analysis (COA) with batch-specific results from HPLC, NMR, and other relevant techniques is available for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment to maintain product integrity and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.