Description

4-(6,7-Dimethoxy-1,2,3,4-Tetrahydro-Isoquinolin-1-Yl)-Butan-1-Ol CAS NO 148204-33-5 is a high-purity synthetic intermediate featuring a tetrahydroisoquinoline core with a functionalized butanol side chain. This compound is valued for its role as a critical building block in the synthesis of complex pharmaceutical molecules, particularly those targeting neurological and cardiovascular pathways. It is essential for research and development chemists, process scale-up teams, and manufacturers in the pharmaceutical and fine chemical industries seeking reliable, high-quality intermediates for advanced API production.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds with tetrahydroisoquinoline pharmacophores.
• Neurological Research: Used in the development of potential therapeutic agents for central nervous system (CNS) disorders.
• Cardiovascular Drug Synthesis: Serves as a building block for candidates in cardiovascular disease research.
• Alkaloid Analog Production: Facilitates the creation of novel tetrahydroisoquinoline-based alkaloid analogs for biological screening.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for efficient commercial-scale manufacturing.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing of specialized organic molecules.

Basic Information

Product Name	4-(6,7-Dimethoxy-1,2,3,4-Tetrahydro-Isoquinolin-1-Yl)-Butan-1-Ol
CAS No.	148204-33-5
Molecular Formula	C₁₅H₂₃NO₃
Molecular Weight	265.35 g/mol
Synonyms	1-(4-Hydroxybutyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline; 6,7-Dimethoxy-1-(4-hydroxybutyl)-1,2,3,4-tetrahydroisoquinoline; 4-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-1-yl)butan-1-ol; 148204-33-5; Tetrahydroisoquinoline butanol derivative
EINECS	Contact for details

Quality Control

Our 4-(6,7-Dimethoxy-1,2,3,4-Tetrahydro-Isoquinolin-1-Yl)-Butan-1-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for pharmaceutical intermediate applications. Certificates of Analysis (COA) documenting all critical quality attributes are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.