Description

3-(Chloromethyl)Isoquinoline is a versatile and reactive heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in the chloromethyl group, which serves as a key handle for further functionalization, enabling the construction of complex molecular architectures. This intermediate is particularly valuable for researchers and manufacturers in the pharmaceutical, agrochemical, and material science sectors, where it is used to develop novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various bioactive molecules, including potential kinase inhibitors, anticancer agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the isoquinoline scaffold for biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Material Science Research: Employed in the synthesis of organic semiconductors, luminescent materials, and metal-organic frameworks (MOFs) due to its planar, aromatic structure.
• Chemical Biology Probes: Useful for constructing molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	3-(Chloromethyl)Isoquinoline
CAS No.	147937-36-8
Molecular Formula	C10H8ClN
Molecular Weight	177.63 g/mol
Synonyms	Isoquinoline, 3-(chloromethyl)-; 3-Chloromethylisoquinoline; (Isoquinolin-3-yl)methyl chloride; 3-(Chloromethyl)isoquinoline; 147937-36-8
EINECS	Contact for details

Quality Control

Our 3-(Chloromethyl)Isoquinoline is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.