Description

1-(2-Thienylcarbonyl)Piperidine-4-Carboxylic Acid (Saltdata: Free) is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure combining thiophene and piperidine motifs. This compound matters for its critical role as a versatile building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. Pharmaceutical R&D and fine chemical manufacturers need this material for developing new therapeutic agents, where its precise chemical framework enables the creation of molecules with specific biological activity.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially for neurological and psychiatric disorders.
• Organic Synthesis Reagent: Used in research-scale and process chemistry for constructing complex heterocyclic compounds.
• Ligand and Catalyst Precursor: Serves as a starting material for developing specialized ligands in catalytic and medicinal chemistry applications.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Academic and Industrial R&D: Utilized in discovery chemistry programs within universities, research institutes, and corporate R&D departments.

Basic Information

Product Name	1-(2-Thienylcarbonyl)Piperidine-4-Carboxylic Acid (Saltdata: Free)
CAS No.	147636-34-8
Molecular Formula	C11H13NO3S
Molecular Weight	239.29 g/mol
Synonyms	4-Piperidinecarboxylic acid, 1-(2-thienylcarbonyl)-; 1-(Thiophene-2-carbonyl)piperidine-4-carboxylic acid; 1-(2-Thienylcarbonyl)-4-piperidinecarboxylic acid; 1-(Thiophen-2-ylcarbonyl)piperidine-4-carboxylic acid; 1-(2-Thiophenecarbonyl)piperidine-4-carboxylic acid; 147636-34-8; Piperidine-4-carboxylic acid, 1-(2-thienylcarbonyl)-
EINECS	Contact for details

Quality Control

Our production of 1-(2-Thienylcarbonyl)Piperidine-4-Carboxylic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly sealed to protect the contents from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.