Description

tert-Butyl 6-Bromo-1H-Indole-1-Carboxylate is a high-purity, protected indole derivative that serves as a critical synthetic intermediate in advanced organic synthesis. Its primary value lies in providing a versatile, reactive scaffold for constructing complex heterocyclic molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working in the pharmaceutical, agrochemical, and fine chemical industries who require reliable building blocks for drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Medicinal Chemistry Research: Used in the exploration of structure-activity relationships (SAR) and the development of indole-based bioactive molecules due to its reactive bromine and protected nitrogen.
• Agrochemical Synthesis: Serves as a precursor in the development of new crop protection agents and pesticides that utilize the indole core structure.
• Fine Chemical Production: Employed in the multi-step synthesis of complex organic compounds, dyes, and functional materials.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic synthesis, including cross-coupling reactions and heterocycle functionalization.

Basic Information

Product Name	tert-Butyl 6-Bromo-1H-Indole-1-Carboxylate
CAS No.	147621-26-9
Molecular Formula	C13H14BrNO2
Molecular Weight	296.16 g/mol
Synonyms	6-Bromo-1H-indole-1-carboxylic acid tert-butyl ester; 1-Boc-6-bromoindole; tert-Butyl 6-bromoindole-1-carboxylate; 6-Bromo-1-(tert-butoxycarbonyl)indole; 1-N-Boc-6-bromoindole; 6-Bromoindole-1-carboxylic acid tert-butyl ester; Boc-6-bromoindole; 147621-26-9
EINECS	Contact for details

Quality Control

Our tert-Butyl 6-Bromo-1H-Indole-1-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with the standards expected in pharmaceutical intermediate supply chains.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.