Description

6-(4-Fluorophenyl)Indole CAS NO 147621-16-7 is a high-purity fluorinated indole derivative, a crucial building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of pharmaceuticals and agrochemicals, where the fluorine atom and indole scaffold impart desirable biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of drug candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the fluorophenylindole structure.
• Material Science Research: Serves as a monomer or functional unit in the creation of organic semiconductors, liquid crystals, and advanced polymers.
• Academic & R&D Laboratories: Employed in methodological studies and as a standard in fluorination chemistry and heterocyclic compound research.
• Fluorescent Probe Development: Utilized in the design of molecular probes and sensors due to the photophysical properties of the indole core.

Basic Information

Product Name	6-(4-Fluorophenyl)Indole
CAS No.	147621-16-7
Molecular Formula	C14H10FN
Molecular Weight	211.24 g/mol
Synonyms	6-(4-Fluorophenyl)-1H-indole; 4-(1H-Indol-6-yl)fluorobenzene; 1H-Indole, 6-(4-fluorophenyl)-; 6-(p-Fluorophenyl)indole; 6-(4-Fluorophenyl)-1H-indole; 147621-16-7; 6-(4-Fluorophenyl)indole
EINECS	Contact for details

Quality Control

Our 6-(4-Fluorophenyl)Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.