Description

3-Amino-3-(3,4-Dichloro-Phenyl)-Propan-1-Ol CAS NO 147611-61-8 is a high-purity, functionalized amino alcohol building block featuring a dichlorophenyl substituent. This compound is of significant commercial interest as a key chiral intermediate in the synthesis of complex active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of central nervous system (CNS) drugs, antidepressants, and other bioactive molecules.
• Agrochemical Synthesis: Serves as a precursor in the manufacturing of advanced herbicides and fungicides, leveraging the dichlorophenyl moiety for enhanced activity.
• Ligand and Catalyst Development: Used in organic chemistry research to create novel chiral ligands for asymmetric catalysis.
• Fine Chemical Production: Employed in the multi-step synthesis of complex dyes, pigments, and other high-value specialty chemicals.
• Academic & Contract Research: A valuable reagent for medicinal chemistry programs and process development in academic and CRO/CMO settings.

Basic Information

Product Name	3-Amino-3-(3,4-Dichloro-Phenyl)-Propan-1-Ol
CAS No.	147611-61-8
Molecular Formula	C9H11Cl2NO
Molecular Weight	220.10 g/mol
Synonyms	3-Amino-3-(3,4-dichlorophenyl)-1-propanol; 3-Amino-3-(3,4-dichlorophenyl)propan-1-ol; 1-Propanol, 3-amino-3-(3,4-dichlorophenyl)-; (3,4-Dichlorophenyl)alaninol; 3-(3,4-Dichlorophenyl)-3-aminopropan-1-ol; β-Amino-β-(3,4-dichlorophenyl)propanol; 147611-61-8
EINECS	Contact for details

Quality Control

Our 3-Amino-3-(3,4-Dichloro-Phenyl)-Propan-1-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for pharmaceutical and agrochemical applications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.