Description

5-Fluoro-3-(1-Piperazinylmethyl)Indole is a high-purity, advanced pharmaceutical intermediate featuring a unique indole-piperazine hybrid structure. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel bioactive molecules targeting central nervous system (CNS) disorders. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially for neurological and psychiatric applications.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its privileged scaffold.
• CNS Drug Development: Serves as a core structure for developing ligands for serotonin, dopamine, or other neurotransmitter receptors.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target validation.
• Custom Synthesis: Starting material for the custom manufacturing of complex, high-value specialty chemicals for preclinical studies.

Basic Information

Product Name	5-Fluoro-3-(1-Piperazinylmethyl)Indole
CAS No.	147595-45-7
Molecular Formula	C13H16FN3
Molecular Weight	233.29 g/mol
Synonyms	5-Fluoro-3-(piperazin-1-ylmethyl)-1H-indole; 1H-Indole, 5-fluoro-3-(1-piperazinylmethyl)-; 5-Fluoro-3-piperazin-1-ylmethyl-1H-indole; 3-(Piperazin-1-ylmethyl)-5-fluoro-1H-indole; 5-Fluoro-3-(piperazin-1-ylmethyl)indole; 147595-45-7; 5-Fluoro-3-(1-piperazinylmethyl)-1H-indole
EINECS	Contact for details

Quality Control

Our 5-Fluoro-3-(1-Piperazinylmethyl)Indole is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive analytical data, including HPLC chromatograms and NMR spectra, to support your project requirements. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with every batch and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.