Description

Alpha,α-Bis(Trimethylsilyl)-tert-Butylketimine is a specialized organosilicon compound that serves as a versatile silylating agent and protected ketimine synthon in advanced organic synthesis. Its primary value lies in its ability to introduce the bulky bis(trimethylsilyl) group, which can act as a protective moiety or direct the course of subsequent reactions. This high-purity intermediate is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Used in the synthesis of complex drug candidates, particularly where steric protection or specific nitrogen functionality is required.
• Agrochemical Synthesis: Serves as a key building block for creating novel pesticides and herbicides with tailored properties.
• Organometallic Chemistry: Acts as a ligand precursor or a reagent in the preparation of metal-organic complexes for catalysis.
• Advanced Material Research: Employed in the development of silicon-containing polymers, coatings, and specialty chemicals.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or a precursor to chiral amines in stereoselective transformations.
• Protecting Group Strategy: The tert-butylketimine group provides a stable protected form of a ketone or amine for multi-step synthetic sequences.

Basic Information

Product Name	Alpha,α-Bis(Trimethylsilyl)-tert-Butylketimine
CAS No.	147227-26-7
Molecular Formula	C13H31NSi2
Molecular Weight	257.57 g/mol
Synonyms	N-(tert-Butyl)-1,1,1,3,3,3-hexamethyl-2-(trimethylsilyl)disilan-2-imine; 2,2-Bis(trimethylsilyl)-N-tert-butylacetimidamide; tert-Butyl [bis(trimethylsilyl)]ketimine; (tert-Butylimino)bis(trimethylsilane); α,α-Bis(trimethylsilyl)-N-tert-butylketimine
EINECS	Contact for details

Quality Control

Our Alpha,α-Bis(Trimethylsilyl)-tert-Butylketimine is manufactured under controlled conditions to ensure batch-to-batch consistency and high purity suitable for research and process-scale applications. All products undergo rigorous quality testing, including assay and impurity profiling by GC/HPLC and NMR, to ensure compliance with stringent specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and safety parameters is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (argon or nitrogen) to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.