Description

(4S,6S)-4H-Thieno[2,3-B]-Thiopyran-4-Ol-5,6-Dihydro-6-Methyl-7,7-Dioxide is a high-purity, stereochemically defined heterocyclic sulfone compound with significant synthetic utility. This molecule serves as a critical chiral building block and advanced intermediate in the development of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical companies engaged in asymmetric synthesis and medicinal chemistry programs targeting complex therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Asymmetric Synthesis: Utilized as a stereocontrolled building block for constructing complex molecular architectures with defined three-dimensional configurations.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization processes due to its unique fused thiophene-thiopyran scaffold.
• Process Chemistry Development: Serves as a reference standard or starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) guidelines.
• Academic Research: Used in university and institutional labs for methodological development in organic synthesis and heterocyclic chemistry.
• Chemical Library Synthesis: Incorporated into diverse compound libraries for high-throughput screening (HTS) in drug discovery.

Basic Information

Product Name	(4S,6S)-4H-Thieno[2,3-B]-Thiopyran-4-Ol-5,6-Dihydro-6-Methyl-7,7-Dioxide
CAS No.	147128-77-6
Molecular Formula	C9H10O3S2
Molecular Weight	230.31 g/mol
Synonyms	(4S,6S)-4H-Thieno[2,3-b]thiopyran-4-ol, 5,6-dihydro-6-methyl-, 7,7-dioxide; (4S,6S)-6-Methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-ol 7,7-Dioxide; (4S-cis)-5,6-Dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-4-ol 7,7-Dioxide; (4S,6S)-Dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-4-ol 7,7-Dioxide; Thienothiopyranol Sulfone Derivative; Chiral Thienothiopyran Sulfone; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our production of (4S,6S)-4H-Thieno[2,3-B]-Thiopyran-4-Ol-5,6-Dihydro-6-Methyl-7,7-Dioxide adheres to stringent quality protocols suitable for research and pharmaceutical development. Each batch undergoes comprehensive analytical characterization, including chiral purity verification by HPLC, to ensure consistent stereochemical integrity and chemical purity. Certificates of Analysis (COA) detailing identity, assay, chiral purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (4S,6S)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.