Description

3-Chlorothiophene-2-Carboxamide is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique thiophene core enables precise molecular modifications. It is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the chlorothiophene moiety.
• Material Science Research: Serves as a monomer or functional unit in the development of conductive polymers, organic semiconductors, and advanced organic electronic materials.
• Chemical Biology & Proteomics: Employed as a versatile scaffold for creating molecular probes, enzyme inhibitors, and tool compounds for biological pathway analysis.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring specific, high-value heterocyclic structures.

Basic Information

Product Name	3-Chlorothiophene-2-Carboxamide
CAS No.	147123-68-0
Molecular Formula	C5H4ClNOS
Molecular Weight	161.61 g/mol
Synonyms	2-Carbamoyl-3-chlorothiophene; 3-Chloro-2-thiophenecarboxamide; 3-Chlorothiophene-2-carboxylic acid amide; 3-Chloro-2-carbamoylthiophene; 3-Chlorothiophene-2-carboxylic acid, amide; 3-Chloro-2-thiophenecarboxylic acid amide; 3-Chlorothiophene-2-carboxylic acid, amide; 3-Chloro-2-thiophenecarboxamide
EINECS	Contact for details

Quality Control

Our 3-Chlorothiophene-2-Carboxamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to verify identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support cGMP and ISO 9001 compliant production for pharmaceutical-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.