Description

(4R,6S)-5,6-Dihydro-4-Hydroxy-6-Methylthieno[2,3-B]Thiopyran CAS NO 147086-80-4 is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry and fused heterocyclic structure. This compound is of significant commercial importance as a key chiral building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the global pharmaceutical and fine chemical industries for the development and production of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of complex drug molecules, particularly in the research and development of new chemical entities.
• API Synthesis: Used as a key building block in the multi-step synthesis of proprietary active pharmaceutical ingredients, leveraging its defined stereocenters.
• Medicinal Chemistry Research: Serves as a valuable scaffold in drug discovery programs for creating libraries of compounds with potential biological activity.
• Process Development: Employed in the scale-up and optimization of synthetic routes for pharmaceutical manufacturing under GMP conditions.
• Asymmetric Synthesis: Utilized in reactions requiring high enantioselectivity due to its fixed (4R,6S) configuration.
• Fine Chemical Production: Acts as a precursor for other specialty chemicals and complex organic molecules used in various high-value applications.

Basic Information

Item	Details
Product Name	(4R,6S)-5,6-Dihydro-4-Hydroxy-6-Methylthieno[2,3-B]Thiopyran
CAS No.	147086-80-4
Molecular Formula	C8H10O1S2
Molecular Weight	186.29 g/mol
Synonyms	(4R,6S)-5,6-Dihydro-4-hydroxy-6-methylthieno[2,3-b]thiopyran; (4R-cis)-5,6-Dihydro-4-hydroxy-6-methylthieno[2,3-b]thiopyran; (4R,6S)-5,6-Dihydro-4-hydroxy-6-methylthieno[2,3-b]thiopyran-2-carboxylic acid methyl ester intermediate; Thieno[2,3-b]thiopyran derivative; CAS 147086-80-4
EINECS	Contact for details

Quality Control

Our (4R,6S)-5,6-Dihydro-4-Hydroxy-6-Methylthieno[2,3-B]Thiopyran is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% de
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.