Description

2-Chloromethyl-3H-Thieno[3,2-D]Pyrimidin-4-One is a high-value heterocyclic building block and key synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for advanced organic synthesis and drug discovery programs.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential therapeutic agents, particularly kinase inhibitors and other small-molecule drugs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the thienopyrimidine scaffold's bioactivity.
• Organic Synthesis Building Block: Serves as a versatile electrophile for alkylation reactions and for constructing fused heterocyclic systems in medicinal chemistry.
• Material Science Research: Investigated as a monomer or precursor for creating novel organic electronic materials and functional polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target validation.

Basic Information

Product Name	2-Chloromethyl-3H-Thieno[3,2-D]Pyrimidin-4-One
CAS No.	147005-91-2
Molecular Formula	C7H5ClN2OS
Molecular Weight	200.64 g/mol
Synonyms	2-(Chloromethyl)-3H-thieno[3,2-d]pyrimidin-4-one; 2-(Chloromethyl)thieno[3,2-d]pyrimidin-4(3H)-one; 4H-Thieno[3,2-d]pyrimidin-4-one, 2-(chloromethyl)-3H-; Thieno[3,2-d]pyrimidin-4(3H)-one, 2-(chloromethyl)-; CAS 147005-91-2
EINECS	Contact for details

Quality Control

Our 2-Chloromethyl-3H-Thieno[3,2-D]Pyrimidin-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. Handle and store under an inert atmosphere if prolonged storage is required.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.