Description

(S)-4,5-Isopropylidene-2-Pentenyl Chloride is a high-value chiral building block and key synthetic intermediate. Its defined stereochemistry and reactive functional groups make it essential for constructing complex molecular architectures with precise spatial orientation. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug discovery and development.
• Agrochemical Synthesis: Used in the production of advanced chiral pesticides and herbicides, where stereochemistry significantly impacts biological activity and environmental profile.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in the development and study of new asymmetric catalytic reactions.
• Fine Chemical Manufacturing: Employed in the multi-step synthesis of complex flavors, fragrances, and specialty chemicals requiring high enantiomeric purity.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic synthesis, including cross-coupling reactions, nucleophilic substitutions, and cyclization strategies.

Basic Information

Product Name	(S)-4,5-Isopropylidene-2-Pentenyl Chloride
CAS No.	146986-69-8
Molecular Formula	C8H13ClO
Molecular Weight	160.64 g/mol
Synonyms	(S)-4,5-O-Isopropylidene-2-pentenyl Chloride; (S)-4,5-O-Isopropylidene-2-penten-1-yl Chloride; (S)-2-(Chloromethyl)-4,4-dimethyl-2-vinyl-1,3-dioxolane; (S)-4,5-Isopropylidene-2-pentenyl Chloride; (S)-2-Vinyl-4,4-dimethyl-2-chloromethyl-1,3-dioxolane; (S)-2-Chloromethyl-4,4-dimethyl-2-vinyl-1,3-dioxolane
EINECS	Contact for details

Quality Control

Our (S)-4,5-Isopropylidene-2-Pentenyl Chloride is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity (typically ≥97% by GC/HPLC), enantiomeric excess (typically ≥99% ee), and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.