Description

Pirbuterol Hydrochloride is a selective β-2 adrenergic receptor agonist, a key pharmaceutical intermediate and active ingredient. Its primary commercial value lies in its bronchodilatory properties, making it essential for respiratory therapeutic applications. This compound is critical for pharmaceutical manufacturers and research institutions developing treatments for asthma, chronic obstructive pulmonary disease (COPD), and other bronchospastic conditions.

Application

• Pharmaceutical Active Ingredient (API): Primary use as the active component in bronchodilator medications.
• Respiratory Drug Formulation: Formulated into metered-dose inhalers (MDIs), dry powder inhalers (DPIs), and nebulizer solutions for asthma and COPD management.
• Reference Standard: Serves as a high-purity chemical standard for analytical testing, quality control, and regulatory compliance in pharmaceutical labs.
• Clinical Research & Development: Used in preclinical and clinical studies to investigate new therapeutic delivery systems and efficacy.
• Generic Drug Manufacturing: A vital raw material for the production of generic versions of pirbuterol-based pharmaceuticals.
• Biochemical Research: Employed in pharmacological studies to understand β-2 adrenergic receptor mechanisms and signaling pathways.

Basic Information

Product Name	Pirbuterol Hydrochloride
CAS No.	146621-71-8
Molecular Formula	C12H20N2O3 • HCl
Molecular Weight	276.76 g/mol (Free base: 240.30 g/mol)
Synonyms	Pirbuterol HCl; (±)-Pirbuterol Hydrochloride; 2-Hydroxy-5-((1RS)-1-hydroxy-2-((1,1-dimethylethyl)amino)ethyl)pyridine hydrochloride; CP-24314-1; PBH; 3-Pyridinemethanol, α6-[[(1,1-dimethylethyl)amino]methyl]-5-hydroxy-, hydrochloride (1:1), (±)-; Exirel (trade name related)
EINECS	Contact for details

Quality Control

Our Pirbuterol Hydrochloride is manufactured and tested under strict quality management systems. We provide material that meets high-purity standards suitable for pharmaceutical research and development. Comprehensive testing includes identity, assay, impurity profiling, and residual solvent analysis. A Certificate of Analysis (COA) is provided with each batch, detailing all test results against established specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.