Description

Pirbuterol Hydrochloride is a selective β-2 adrenergic receptor agonist, primarily utilized as a key pharmaceutical intermediate or active pharmaceutical ingredient (API). Its value lies in its bronchodilatory properties, making it essential for the development of respiratory medications. This compound is critically needed by pharmaceutical manufacturers and research institutions focused on creating treatments for asthma, chronic obstructive pulmonary disease (COPD), and other bronchospastic conditions.

Application

• Pharmaceutical API Synthesis: Primary use as the active ingredient in the formulation of bronchodilator medications.
• Respiratory Drug Development: Critical intermediate in R&D for new asthma and COPD therapeutics.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical labs.
• Clinical Research Material: Used in preclinical and clinical studies investigating β-2 agonist efficacy and safety profiles.
• Generic Drug Manufacturing: Essential for producing generic versions of pirbuterol-based inhalers and tablets.
• Biochemical Research: Tool compound for studying adrenergic receptor mechanisms and signal transduction pathways.

Basic Information

Product Name	Pirbuterol Hydrochloride
CAS No.	146621-68-3
Molecular Formula	C12H20N2O3 • HCl
Molecular Weight	276.76 g/mol (Free base: 240.30)
Synonyms	Pirbuterol HCl; (±)-Pirbuterol Hydrochloride; 2-tert-Butylamino-1-(5-hydroxy-6-hydroxymethyl-2-pyridyl)ethanol Hydrochloride; 3-Hydroxy-α-[(tert-butylamino)methyl]-5-(hydroxymethyl)-2-pyridinemethanol Hydrochloride; CP-24314-1; PBH; (RS)-Pirbuterol Hydrochloride
EINECS	Contact for details

Quality Control

Our Pirbuterol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by IR and NMR, to ensure it meets stringent pharmaceutical-grade specifications. Certificates of Analysis (COA) documenting full compliance are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.