Description

Pirbuterol is a selective β-2 adrenergic receptor agonist, a class of compounds widely recognized for their bronchodilatory effects. This high-purity active pharmaceutical ingredient (API) is essential for the development and manufacturing of advanced respiratory therapeutics. It is primarily utilized by pharmaceutical companies and research institutions focused on creating treatments for asthma, chronic obstructive pulmonary disease (COPD), and other bronchospastic conditions.

Application

• Pharmaceutical API: Primary use as the active ingredient in the formulation of metered-dose inhalers (MDIs), dry powder inhalers (DPIs), and nebulizer solutions for respiratory relief.
• Bronchodilator Formulations: Key component in medications designed to treat and manage symptoms of asthma and reversible airway obstruction.
• COPD Management: Incorporated into therapeutic regimens for chronic obstructive pulmonary disease to alleviate bronchoconstriction.
• Research & Development: Serves as a critical reference standard and building block in pharmacological research for new adrenergic agents.
• Veterinary Pharmaceuticals: Potential application in veterinary medicine for treating respiratory conditions in animals.
• Analytical Standard: Used as a high-purity standard in quality control laboratories for HPLC, GC, or spectroscopic analysis of drug products.

Basic Information

Product Name	Pirbuterol
CAS No.	146621-66-1
Molecular Formula	C12H20N2O3
Molecular Weight	240.30 g/mol
Synonyms	Pirbuterol; (±)-Pirbuterol; 2-tert-Butylamino-1-(5-hydroxy-6-hydroxymethyl-2-pyridyl)ethanol; 5-(1-Hydroxy-2-tert-butylaminoethyl)-6-hydroxymethyl-2-pyridinol; CP-24314-1; Exirel (trade name); Pyrbuterol
EINECS	Contact for details

Quality Control

Our Pirbuterol CAS NO 146621-66-1 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for identity, purity, and potency, aligning with ICH guidelines. A Certificate of Analysis (COA) detailing results for assay, related substances, residual solvents, and other critical parameters is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Water (KF)	≤ 1.0% w/w
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.