Description

Boc-L-7-Azatrp is a protected derivative of the non-natural amino acid 7-azatryptophan, featuring a tert-butoxycarbonyl (Boc) group on the α-amino function. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled incorporation of the unique 7-azaindole moiety into peptide chains. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel bioactive peptides, peptidomimetics, and chemical probes, where the 7-azatryptophan side chain can modulate interactions and properties.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a Boc-protected amino acid for the sequential assembly of complex peptides.
• Medicinal Chemistry Research: For the synthesis of peptide-based drug candidates and libraries targeting various biological pathways.
• Bioconjugation & Probe Development: Incorporation into peptides used as fluorescent probes, affinity tags, or for protein labeling studies.
• Structure-Activity Relationship (SAR) Studies: To investigate the role of tryptophan analogs in peptide-receptor binding and stability.
• Academic & Industrial R&D: Fundamental research in peptide science, chemical biology, and material science.

Basic Information

Product Name	Boc-L-7-Azatrp
CAS No.	146610-21-1
Molecular Formula	C₁₇H₂₁N₃O₄
Molecular Weight	331.37 g/mol
Synonyms	Boc-7-aza-L-tryptophan; (S)-2-((tert-Butoxycarbonyl)amino)-3-(1H-pyrrolo[2,3-b]pyridin-3-yl)propanoic acid; Boc-L-7-azatryptophan; tert-Butyloxycarbonyl-7-aza-L-tryptophan; N-α-Boc-7-aza-L-tryptophan; Boc-7-Azatrp-OH; N-Boc-7-azatryptophan; 7-Azatrp(Boc)-OH
EINECS	Contact for details

Quality Control

Our Boc-L-7-Azatrp CAS NO 146610-21-1 is manufactured under strict quality control protocols to ensure high chemical purity and batch-to-batch consistency, suitable for sensitive research and development applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. The product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.