Description

1,4-Diazabicyclo[2.2.2]Octan-2-One(9Ci) is a specialized bicyclic organic compound featuring a unique bridged structure that combines amide and tertiary amine functionalities. This molecular architecture makes it a valuable intermediate and building block in advanced synthetic chemistry, particularly for the development of pharmaceuticals and functional materials. It is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring complex, nitrogen-containing heterocycles.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides where its rigid structure can contribute to biological activity.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Chemistry: Employed in the synthesis of specialty polymers and dendrimers, where it can act as a branching point or functional monomer.
• Academic & R&D: A valuable reagent for methodological research in organic synthesis and medicinal chemistry programs at universities and corporate R&D centers.

Basic Information

Product Name	1,4-Diazabicyclo[2.2.2]Octan-2-One(9Ci)
CAS No.	146562-83-6
Molecular Formula	C7H12N2O
Molecular Weight	140.18 g/mol
Synonyms	1,4-Diazabicyclo[2.2.2]octan-2-one; 2-Oxo-1,4-diazabicyclo[2.2.2]octane; DABCO lactam; Triethylenediamine lactam; 1,4-Diazabicyclo[2.2.2]octane-2-one; TEDA lactam; 2-Aza-5-oxabicyclo[2.2.2]octane (related structure); Bicyclic urea derivative
EINECS	Contact for details

Quality Control

Our 1,4-Diazabicyclo[2.2.2]Octan-2-One(9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (by HPLC), residual solvents, and related substances are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong acids. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.