Description

Methyl 3-[(2-Chloroacetyl)Amino]Thiophene-2-Carboxylate is a high-purity, synthetically valuable heterocyclic building block. This compound is a key intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical research sectors. It is primarily sought after by R&D chemists and process development scientists for constructing novel thiophene-based scaffolds with potential biological activity. Its defined structure and reactivity make it essential for targeted synthesis programs.

Application

• Pharmaceutical Intermediate: A crucial precursor in the research and development of new active pharmaceutical ingredients (APIs), particularly those containing the thiophene moiety.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science Research: Serves as a building block for advanced organic materials, such as organic semiconductors and conductive polymers.
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A specified starting material for custom synthesis projects and scale-up processes under cGMP or ISO guidelines.
• Academic & Institutional Research: Used in universities and research institutes for methodological development and exploration of new chemical spaces.

Basic Information

Item	Detail
Product Name	Methyl 3-[(2-Chloroacetyl)Amino]Thiophene-2-Carboxylate
CAS No.	146381-88-6
Molecular Formula	C8H8ClNO3S
Molecular Weight	233.67 g/mol
Synonyms	Methyl 3-(2-chloroacetamido)thiophene-2-carboxylate; 2-Carbomethoxy-3-(2-chloroacetamido)thiophene; 3-[(2-Chloroacetyl)amino]-2-thiophenecarboxylic acid methyl ester; Methyl 3-amino-2-thiophenecarboxylate, N-(2-chloroacetyl)-; Thiophene-2-carboxylic acid, 3-[(2-chloroacetyl)amino]-, methyl ester
EINECS	Contact for details

Quality Control

Every batch of Methyl 3-[(2-Chloroacetyl)Amino]Thiophene-2-Carboxylate is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment. Our quality protocols are designed to support regulatory filings and ensure batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.