Description

2,4-Thiophenedicarboxylic Acid, 5-[(2-Chloroacetyl)Amino]-3-Methyl-, Diethyl Ester is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmacologically active molecules, particularly within medicinal chemistry research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme inhibitors or receptor modulators.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its unique thiophene scaffold.
• Organic Synthesis Building Block: Employed in academic and industrial research for constructing complex heterocyclic compounds and functional materials.
• Material Science Research: Potential intermediate for the synthesis of organic semiconductors or ligands for catalytic systems due to its electron-rich thiophene core.
• Chemical Biology Probes: Can be utilized to develop molecular probes for studying biological processes, given its reactive chloroacetyl and ester functional groups.

Basic Information

Product Name	2,4-Thiophenedicarboxylic Acid, 5-[(2-Chloroacetyl)Amino]-3-Methyl-, Diethyl Ester
CAS No.	146381-87-5
Molecular Formula	C14H16ClNO5S
Molecular Weight	345.80 g/mol
Synonyms	Diethyl 5-[(2-chloroacetamido)-3-methylthiophene-2,4-dicarboxylate; 3-Methyl-5-[(2-chloroacetyl)amino]thiophene-2,4-dicarboxylic Acid Diethyl Ester; 5-(2-Chloroacetamido)-3-methylthiophene-2,4-dicarboxylic Acid Diethyl Ester; 2,4-Thiophenedicarboxylic acid, 5-[(2-chloroacetyl)amino]-3-methyl-, diethyl ester; 146381-87-5; AKOS BRN 0975; 5-(2-Chloroacetamido)-3-methyl-2,4-thiophenedicarboxylic Acid Diethyl Ester
EINECS	Contact for details

Quality Control

Our 2,4-Thiophenedicarboxylic Acid, 5-[(2-Chloroacetyl)Amino]-3-Methyl-, Diethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.