Description

Ethyl 2-((5,6-Dimethyl-4-Oxo-3,4-Dihydrothieno[2,3-D]Pyrimidin-2-Yl)Thio)Acetate is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is of significant commercial importance as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular frameworks. It is primarily sought after by research institutions, custom synthesis laboratories, and pharmaceutical manufacturers engaged in developing new chemical entities.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates, especially those with thienopyrimidine cores.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Custom Synthesis: Serves as a specialized starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.
• Biochemical Tool Compound: Potential use in developing enzyme inhibitors or receptor modulators for biological research and assay development.
• Agrochemical Research: Exploration of its derivatives for potential application in crop protection and pesticide development.

Basic Information

Product Name	Ethyl 2-((5,6-Dimethyl-4-Oxo-3,4-Dihydrothieno[2,3-D]Pyrimidin-2-Yl)Thio)Acetate
CAS No.	146381-74-0
Molecular Formula	C₁₃H₁₄N₂O₃S₂
Molecular Weight	310.39 g/mol
Synonyms	Ethyl (5,6-dimethyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)thioacetate; 2-[(5,6-Dimethyl-4-oxo-3H-thieno[2,3-d]pyrimidin-2-yl)thio]acetic acid ethyl ester; Ethyl 2-((5,6-dimethyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)thio)acetate; Thieno[2,3-d]pyrimidine-2-thioacetic acid ethyl ester derivative; CAS 146381-74-0
EINECS	Contact for details

Quality Control

Our Ethyl 2-((5,6-Dimethyl-4-Oxo-3,4-Dihydrothieno[2,3-D]Pyrimidin-2-Yl)Thio)Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet client-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider inert atmosphere conditions to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.