Description

Glyceryl Trivalproate is a specialized ester derivative of valproic acid, a compound of significant pharmaceutical interest. This chemical serves as a key intermediate or active pharmaceutical ingredient (API) in the development of advanced therapeutic formulations. It is primarily required by research institutions and manufacturers in the pharmaceutical and life sciences sectors for the synthesis of novel drug candidates, particularly those targeting neurological and psychiatric conditions.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of prodrugs and novel valproate derivatives for enhanced drug delivery and efficacy.
• Neurological Research: Used in preclinical and clinical research for developing treatments for epilepsy, bipolar disorder, and migraine prophylaxis.
• Drug Delivery Systems: Employed in the formulation of controlled-release and targeted delivery systems to improve pharmacokinetic profiles.
• Biochemical Research: Serves as a tool compound in studies investigating histone deacetylase (HDAC) inhibition and its effects on gene expression.
• Reference Standard: Utilized as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Glyceryl Trivalproate
CAS No.	146356-76-5
Molecular Formula	C24H42O6
Molecular Weight	426.59 g/mol
Synonyms	1,2,3-Propanetriyl Tris(2-propylpentanoate); Tris(valproyl) Glycerol; Glycerol Trivalproate; Valproic Acid Triglyceride Ester; 2-Propylpentanoic Acid 1,2,3-Propanetriyl Ester; Triglyceryl Valproate; TVG; GTVA
EINECS	Contact for details

Quality Control

Our Glyceryl Trivalproate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, assay, and impurity profiling via HPLC, GC, and NMR, to ensure it meets stringent specifications for pharmaceutical research and development. Certificates of Analysis (COA) documenting purity, related substances, and residual solvents are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.