Description

(2E)-1-(2-Hydroxyphenyl)-3-(Phenyl-D5)-2-Propen-1-One CAS NO 146196-93-2 is a deuterated derivative of a chalcone, a class of compounds known for their significant biological and photophysical properties. This high-purity, isotopically labeled compound is essential for research and development requiring precise molecular tracking and analysis. It is primarily utilized by pharmaceutical researchers, analytical chemists, and material scientists working in advanced spectroscopy, metabolic studies, and the development of organic electronic materials.

Application

• Internal Standard for Quantitative Analysis: Serves as a critical deuterated internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for the accurate quantification of its non-deuterated analog in complex biological matrices.
• Metabolic Pathway Tracing: Used in pharmacokinetic and drug metabolism studies to trace and elucidate metabolic pathways and stability of chalcone-based drug candidates.
• NMR Spectroscopy: Acts as a useful probe in Nuclear Magnetic Resonance (NMR) spectroscopy due to the distinct signal of deuterium, aiding in structural elucidation and mechanistic studies.
• Pharmaceutical Intermediate: Employed as a building block in the synthesis of novel, labeled pharmaceutical compounds for research into anti-inflammatory, anticancer, and antimicrobial agents.
• Material Science Research: Investigated for its potential photophysical properties in the development of organic light-emitting diodes (OLEDs) and nonlinear optical materials.
• Reference Standard: Provides a high-purity certified reference material (CRM) for quality control and method validation in analytical laboratories.

Basic Information

Item	Detail
Product Name	(2E)-1-(2-Hydroxyphenyl)-3-(Phenyl-D5)-2-Propen-1-One
CAS No.	146196-93-2
Molecular Formula	C15H7D5O2
Molecular Weight	229.28 g/mol
Synonyms	2'-Hydroxychalcone-d5; (E)-1-(2-Hydroxyphenyl)-3-(pentadeuteriophenyl)prop-2-en-1-one; 3-(Phenyl-d5)-1-(2-hydroxyphenyl)-2-propen-1-one; Deuterated Chalcone; 2'-Hydroxy-3,4,5,6,2',3',4',5',6'-nonadeuterochalcone; Phenyl-D5 Chalcone Derivative; Isotopically Labeled Chalcone
EINECS	Contact for details

Quality Control

Every batch of our (2E)-1-(2-Hydroxyphenyl)-3-(Phenyl-D5)-2-Propen-1-One is manufactured under strict quality management protocols. We guarantee high chemical and isotopic purity, verified through advanced analytical techniques including NMR, HPLC, and Mass Spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic enrichment, and impurity profile is provided with each shipment to ensure traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.