Description

Flavanone-D5 is a deuterium-labeled analog of the naturally occurring flavanone, a key member of the flavonoid family. This stable isotope-labeled compound is essential for use as an internal standard in quantitative mass spectrometry, ensuring the highest accuracy and reliability in analytical measurements. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, nutraceutical, and food science industries for method development, pharmacokinetic studies, and metabolic profiling.

Application

• Internal Standard for LC-MS/MS Analysis: Critical for the precise quantification of flavanone and related metabolites in complex biological matrices like plasma, serum, and tissue homogenates.
• Pharmacokinetic and Bioavailability Studies: Enables accurate tracking of drug absorption, distribution, metabolism, and excretion (ADME) for flavonoid-based pharmaceuticals and supplements.
• Metabolomics Research: Serves as a stable isotope tracer to elucidate metabolic pathways and flux analysis in plant, microbial, and mammalian systems.
• Food and Beverage Analysis: Used to quantify natural flavanone content and authenticity in citrus juices, herbal products, and functional foods.
• Quality Control and Method Validation: Provides a reference point for ensuring the accuracy, precision, and reproducibility of analytical methods in GLP/GMP environments.
• Doping Control Analysis: Supports the detection and quantification of prohibited substances in sports by providing a reliable isotopic reference.

Basic Information

Product Name	Flavanone-D5
CAS No.	146196-91-0
Molecular Formula	C15H7D5O2
Molecular Weight	227.28 g/mol
Synonyms	2,3-Dihydro-2-phenyl-4H-1-benzopyran-4-one-d5; 2,3-Dihydroflavone-d5; 2-Phenylchroman-4-one-d5; Flavanone (phenyl-d5); Flavanone-d5 (Ring-d5); Deuterated Flavanone; [2H5]-Flavanone; Flavanone (2,3,4,5,6-pentadeutero)
EINECS	Contact for details

Quality Control

Every batch of Flavanone-D5 is manufactured and tested under strict quality management systems. We provide comprehensive analytical data including NMR and Mass Spectrometry to confirm isotopic enrichment and chemical purity. Certificates of Analysis (COA) detailing purity, isotopic purity (D-enrichment), and solvent content are available upon request, supporting compliance in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at 2-8°C under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Chemical Purity (NMR)	Conforms
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.